mike small

Honorary Professorial Fellow
National Heart and Lung Institute
Hammersmith Hospital Campus
Imperial College School of Medicine

Clinical and research interests are pulmonary physiology, lung function, gas exchange, the pulmonary circulation and radioisotope studies.

Particular expertise in analysis and interpretation of the Transfer Factor/diffusing capacity for nitric oxide [TLNO/DLNO] and carbon monoxide [TLCO/DLCO]

Hughes Mike. Editorial. Transfer factor of the lung for carbon monoxide: what is the significance of an abnormal result? Eur Respir J 2021; 58: 2101326. Download

Hughes JMB. Commentary. Medical breakthroughs: chance and opportunity.  Quart J Med 2021; 229-231. Based on Presidential address to Harveian Society of London, 9 November 2016. Copies available via email to This email address is being protected from spambots. You need JavaScript enabled to view it.

Hughes JMB, Pride NB. Examination of the carbon monoxide diffusing capacity (DLCO) in relation to its KCO and VA components. Concise Clinical Review. Amer J Respir Crit Care Med 2012; 186: 132-139. Download

Hughes JMB and Dinh-Xuan AT The TL,NO/TL,CO ratio: physiological significance and clinical implications. Respir Physiol Neurobiol 2017: July 241: 17-22. Download

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