mike small

Honorary Professorial Fellow
National Heart and Lung Institute
Hammersmith Hospital Campus
Imperial College School of Medicine

Clinical and research interests are pulmonary physiology, lung function, gas exchange, the pulmonary circulation and radioisotope studies.

Particular expertise in analysis and interpretation of the Transfer Factor/diffusing capacity for nitric oxide [TLNO/DLNO] and carbon monoxide [TLCO/DLCO]

Hughes JMB, Pride NB. Examination of the carbon monoxide diffusing capacity (DLCO) in relation to its KCO and VA components. Concise Clinical Review. Amer J Respir Crit Care Med 2012; 186: 132-139. Download

Hughes JMB and Dinh-Xuan AT The TL,NO/TL,CO ratio: physiological significance and clinical implications. Respir Physiol Neurobiol 2017: July 241: 17-22. Download

See also:

Hughes JMB Editorial Hypoxic pulmonary vasoconstriction: clinical implications. Eur Respir J 2016; 47: 31-34. Download

Physiology and Practice of Pulmonary Function
reprinted by ARTP, 2011
Click HERE for details
and to order your copy


Feb 2017 Standardisation of the DLNO (see Selected Publications [Transfer Factor for TLNO])

Jan 2011 New book reprinted: click HERE to order a copy



Tel: 44 (0) 208 876 6822

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