Transfer Factor/diffusing capacity for carbon monoxide (TLCO/DLCO)


Hughes JMB. Physiology and Practice of Pulmonary Function. Association for Respiratory Technology and Physiology [] (publisher), 2009. reprinted 2011, Pp 123-147, 273-281.

Chapters, reviews, editorials

Hughes JMB, Borland CDR. The centenary of the transfer factor for carbon monoxide (TLCO). Marie Keogh's legacy. Thorax 2015; 70(4): 391-4. Download
Hughes JMB, Pride NB
. Examination of the carbon monoxide diffusing capacity (DLCO) in relation to its KCO and VA components. Concise Clinical Review. Amer J Respir Crit Care Med 2012; 186: 132–139. Download
Hughes JMB, Pride NB. In defence of the carbon monoxide transfer coefficient KCO (TL/ VA). Point of view. Eur Respir J 2001; 17: 168-174. Download
Hughes JMB. Pulmonary gas exchange. In: Lung Function Testing. R Gosselink and H Stam eds. European Respiratory Monograph, Vol 10, 2005. pp. 106-126.
Hughes JMB. The single breath transfer factor (TL,CO) and the transfer coefficient (KCO): a window onto the pulmonary microcirculation. Clin Physiol & Func Im 2003; 23: 63-71. Download

Original articles

Hughes JMB, Bates DV. Historical review: the carbon monoxide diffusing capacity and its membrane (DM) and red cell (Θ Vc) components. Respir Physiol Neurobiol. 2003; 138: 115-142. Download
Ewan PW, Jones HA, Rhodes CG, Hughes JMB. Detection of intrapulmonary hemorrhage with carbon monoxide uptake Application in Goodpature's Syndrome. New Engl. J. Med. 1976; 295: 1391-1396. Download
Jones, Hazel A, Clark JC, Davies EE, Forster RE, Hughes JMB. Rate of uptake of carbon monoxide at different inspired concentrations in humans. J. Appl. Physical. 1982; 52: 109-113. Download

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