Intrapulmonary shunting and haemorrhage


Shovlin CL, Jackson JE, Hughes JMB. Pulmonary arteriovenous malformations and other pulmonary vascular abnormalities. In: Textbook of Respiratory Medicine Mason RJ, Boushey HA, Murray JF, Nadel JA eds: Elsevier Saunders. 4th Edn. 2005 pp. 1480-1501.
Hughes JMB. Pulmonary Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. In: Special issue on Pulmonary Vasculitis. ed RN duBois. Seminars in Respiratory and Critical Care Medicine 1997; 19: 79-89..
Hughes JMB. Intrapulmonary shunts: coils to transplantation (College lecture). J.Roy.Coll.Phys 1994; 28: 247-253

Original articles

Rizvi A, Macedo P, Babawale L, Tighe HC, Hughes JMB, Jackson JE, Shovlin CL. Hemoglobin Is a vital determinant of arterial oxygen content in hypoxemic patients with pulmonary arteriovenous malformations. Ann Am Thoracic Soc. 2017 Jun: 14(6); 903-911 Download
Howard LS, Santhirapala V, Murphy K, Mukherjee B, Busbridge M, Tighe HC, Jackson JE, Hughes JMB, Shovlin CL. Cardiopulmonary exercise testing demonstrates maintenance of exercise capacity in patients with hypoxemia and pulmonary arteriovenous malformations. Chest. 2014 Sep; 146(3): 709-18. doi: 10.1378/chest.13-2988. Download
Gupta P, Mordin C, Hughes JM, Shovlin CL, Jackson JE. Pulmonary arteriovenous malformations: effect of embolization on right-to-left shunt, hypoxemia, and exercise tolerance in 66 patients. Am J Roentgenol 2002; 179: 347-55. Download
Thompson RJ, Jackson JE, Peters AM, Dore CJ, Hughes JMB. Sensitivity and specificity of radioisotope right to left shunt measurements and pulse oximetry for the early detection of pulmonary arteriovenous malformations. Chest 1999; 115: 109-113. Download
Whyte MKB, Hughes JMB, Peters AM, Ussov W, Patel S, Burroughs AK. Analysis of intrapulmonary right to left shunt in the hepatopulmonary syndrome. J Hepatol 1998; 29: 85-93. Download
Shovlin CL, Hughes JMB, Scott J, Seidman CE, Seidman JG. Characterization of endoglin and identification of novel mutations in hereditary haemorrhagic telangiectasia. Am J Hum Genet 1997; 61: 68-79. Download
Dutton J, Jackson JE, Peters AM, Ueki J, Ussov W, Hughes JMB. Pulmonary arteriovenous malformations: pathophysiology and treatment with coil embolization. Am J Roentgenol 1995; 165: 1119-1125. Download
Shovlin CL, Winstock AR, Jackson JE, Peters AM, Hughes JMB. Medical complications of pregnancy in hereditary haemorrhagic telengiectasia . Quart J Med 1995; 88: 879-887. Download
Shovlin CL, Hughes JMB, Tuddenham EGD, Temperley I, Perembelon YFN, Scott J, Siedman CE, Seidman JG. A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3. Nature Genetics 1994; 6:205-208. Download
Whyte MKB, Hughes JMB, Jackson JE, Peters AM, Hempleman SC, Jones HA. Cardiopulmonary response to exercise in patients with intrapulmonary vascular shunts. J Appl Physiol 1993; 75: 321-328. Download
Whyte MKB, Peters AM, Hughes JMB, Henderson BL, Bellingan GJ, Jackson JE, Chilvers ER. Quantification of right-to-left shunt at rest and during exercise in patients with pulmonary arteriovenous malformations. Thorax 1992; 47: 790-796. Download
Chilvers ER, Whyte MKB, Jackson JE, Allison DJ, Hughes JMB. Effect of percutaneous transcatheter embolization on pulmonary function, right-to-left shunt, and arterial oxygenation in patients with pulmonary arteriovenous malformations. Am Rev Respir Dis 1990; 142: 420-425. Download
Ewan PW, Jones HA, Rhodes CG, Hughes JMB. Detection of intrapulmonary haemorrhage with carbon monoxide uptake: application in Goodpasture’s Syndrome. N Engl J Med 1976; 295:1391-1396. Download

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